Certainly! Email validation through regular expressions (regex) can be tricky because the RFC 5322 standard for email formats is quite complex, and a regex that completely adheres to this standard can be overly complicated and not very practical for most applications. Instead, for practical purposes, developers often use a simplified regex that covers the vast majority of common email address cases.

Here's a regex pattern that is widely used for email validation in many applications. It balances between complexity and practicality, catching most of the common and valid email formats:

```javascript
const emailRegex = /^[a-zA-Z0-9._-]+@[a-zA-Z0-9.-]+\.[a-zA-Z]{2,}$/;
```

This pattern does the following:
- `^[a-zA-Z0-9._-]+` matches the start of the email address, which must begin with alphanumeric characters, and can include dots, underscores, or hyphens.
- `@` ensures that the `@` symbol is present in the middle.
- `[a-zA-Z0-9.-]+` matches the domain part of the email, which can have alphanumeric characters, dots, or hyphens.
- `\.[a-zA-Z]{2,}$` matches the top-level domain (TLD), ensuring it starts with a dot followed by two or more alphabetical characters.

While this regex will match most common email formats, it's important to note that it might not match all valid email addresses defined by the RFC 5322 standard (for example, quoted strings or domain literals). However, for most practical web and application development scenarios, this regex offers a good balance between validation strength and allowing valid emails through.

If your application requires a more comprehensive validation, consider using a library dedicated to this task, as it can handle more edge cases and ensure compliance with the email address specifications.