The landscape of scientific research is undergoing a seismic shift. Researchers can no longer be content with off-the-shelf tools and materials for conducting breakthrough research. There is an increasing demand for precision, specificity, and customization. This paradigm shift is particularly evident in the realm of cell culture, where the need for tailored cell culture solutions has become as indispensable as a scalpel is to a surgeon.
At the heart of this growing demand lies the recognition that one size does not fit all when it comes to cells. These microscopic building blocks of life are, in fact, as diverse as snowflakes. Each specific type of cell is unique and has its own quirks and requirements. We cannot use DMEM, akin to a one-size-fits-all shoe, to culture cell lines like renal fibroblast. At times like these, we require custom cell culture media that will provide sustenance to these cells with optimized nutrient levels. They offer a tailored environment that caters to the specific needs of each cell type.
In this blog, we will advocate to you how custom cell solutions can help expedite your research, leading to biologically significant results in humans.
Why do we need custom cell culture media and custom cell solutions?
There are various reports that show that media components can significantly affect cell growth, expression profile, transfection efficiency, surface marker expression, and physiology of the cells.
A study published in “THE CELL” in 2016, demonstrated how L-arginine concentrations can impact the metabolic profile and survival of T cells. Another study showed that adding cytokine IL-21 in the cell culture media can significantly improve the transfection efficiency of T-cells.
These studies are just a glimpse of what the literature is telling us about the importance of custom cell culture media. Another level of complication that is often overlooked is the presence or use of primary cells that are required for studies. For instance, you are studying T-cells biology but if you are using immortalized cells, how will they be able to give you results that are similar to physiological conditions? Thus, there is a need for custom cell solution services, which can provide you with human primary cells from healthy donors or donors with specific conditions.
It is a time-consuming process to find a donor, collect the sample, and then expand the primary cells for your experiments. This is all needed to be done while you have to do regular research work. It just creates unnecessary stress for you and your research team. So, what is the solution? It is important to put your trust in the primary cell manufacturers.
Kosheeka: Your Partner in Cell Culture Customization
We at Kosheeka have over a decade of experience providing custom cell solutions to researchers and contract research organizations. Our custom cell culture media are not merely mixtures of chemicals in water; they are meticulously crafted formulations for your cells. Our media are made with special attention to the cells’ specific nutrients, pH levels, osmolarity, sterility, and endotoxin levels.
On the other hand, our custom cell culture media is akin to providing the cell with a carefully balanced, nutrient-rich soil, ensuring optimal growth and vitality. We follow a comprehensive customization plan that is flexible. We work with you to understand your specific requirements, overcoming any challenges that may arise. Our team of scientists is committed to transforming your research aspirations into reality.
With our deep-rooted passion for cellular biology, we are well-equipped to provide you with rare primary cells, develop novel cell lines, or help you create intricate experiments.
Benefits of using custom cell culture media and custom cell solutions
The advantages of using custom cell culture media are manifold. These include:
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Scale-up of the custom recipes with top-quality powdered media.
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Media components are isolated from qualified sources, ensuring GMP-compliance.
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Quick availability of primary cells for your experiments.
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Flexibility to customize existing media for your cell culture experiment.
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Comprehensive regulatory documentation for the cells used in treatment.
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Complete quality check reports to ensure that the cells and media you receive boost cell growth.
Conclusion
Custom cell solutions are quickly becoming the need of the hour as we dive deep into understanding human biology. Using primary cells enables us to make groundbreaking discoveries and develop drugs for therapeutic purposes. Custom cell culture media is crucial for providing the right environment that accelerates cell growth while maintaining physiological similarities with human body cells.
With a decade of experience in providing high-quality custom
cell solutions, Kosheeka is in the perfect position to ensure that your research is ready to go to the next level. For more information, please contact us at +91–965–4321–400 or visit our website.
References
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Geiger R, Rieckmann JC, Wolf T, et al. L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity. Cell. 2016;167(3):829–842.e13. doi:10.1016/j.cell.2016.09.031
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Du L, Nai Y, Shen M, et al. IL-21 Optimizes the CAR-T Cell Preparation Through Improving Lentivirus Mediated Transfection Efficiency of T Cells and Enhancing CAR-T Cell Cytotoxic Activities. Front Mol Biosci. 2021;8:675179. Published 2021 Jun 4. doi:10.3389/fmolb.2021.675179