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Serum IgE Test: Purpose, Procedure, Results, and Normal Range

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Tenet Diagnostic @tenet · Jul 6, 2022
The serum IgE test aids in identifying allergies in our bodies. Immunoglobulin E, often known as IgE, is one of the five different types of antibodies that are found in trace amounts in our blood. The serum IgE test counts all of the IgE antibodies in your blood.

 

The Serum IgE Test is another name for the Serum IgE test. It costs between Rs. 500 and Rs. 1000. You may now order a Serum IgE test from a NABL Certified facility for the lowest pricing. The serum indicates the type of sample needed for the IgE test. Contrary to the Specific IgE test, this one is different. At the same time, the first test counts all antibodies, and the second count the amount of IgE antibodies produced in response to allergens.

 

What is the Purpose of the Serum IgE Test?

 

A serum IgE test identifies illnesses that cause allergies. This examination looks for parasite infection as well. Blood with lower levels of IgE antibodies is considered normal. However, if the amount in your blood exceeds the typical range, you may have an allergy.

 

The following examples illustrate how an IgE test may be used to monitor a patient with a known allergy condition:

 

• Anaphylaxis
• Allergic rhinitis (hay fever)
• Allergic conjunctivitis
• Asthma
• Chronic rhinosinusitis.

 

IgE receptors are found on the surface of allergy cells, acting as critical points for IgE antibodies. An allergic reaction is not always brought on by IgE antibodies attaching to their receptors on allergy cells. Instead, it prepares the allergy cells to respond when enough of the proper allergens are present. 

 

What does IgE Measure?

 

The IgE test calculates the blood's level of IgE (immunoglobulin E). The immune system creates this antibody in reaction to danger. It often only appears in significantly trace concentrations in the blood. It is a part of the immunoglobulin family, including the five immunoglobulin subtypes IgA, IgG, IgM, IgD, and IgE.

 

When the body detects bacteria, viruses, other microbes, or any other unknown things as potentially hazardous foreign antigens to the immune system, plasma cells (specific immune cells) generate immunoglobulins.

 

When a person has an allergic reaction, such as asthma, or when they have a parasite infection, IgE is produced. Plant pollen, eggs, peanuts, bee venom, strawberries, and other allergens are examples of additional allergens.

 

Procedure
A pathology expert will take blood from a vein in your arm in less than five minutes, if not sooner. Then, to determine whether or not you have an allergy, the blood drawn will be used in the final step.
Risks
The test carries no significant risk. However, like any other blood test, this one may leave a bruise where the needle was inserted, and drawing blood will cause discomfort.
Serum IgE Test Results
The individual is probably allergic if the level of IgE is higher than the advised threshold. However, the results of a total IgE test cannot identify the specific allergy you would have. A person with a high whole IgE level is likely to have one or more allergies. The total IgE level will be impacted by the allergy specific IgE level, which will rise after exposure and then fall over time.

 

The specific and total IgE levels should rise during the season when the allergen is present if one has an allergy to a seasonal substance, such as pollen. The specific allergy test now comes into play. This test will identify the exact allergy that a person may have. The following table lists several specific allergens' ranges:

 

Interpretations:

 

IgE < 64.0o kUA/L 
*Reference range may vary from lab to lab
Although the average IgE level can range from 150 to 1,000 UI/ml, 150 to 300 UI/ml is generally considered the upper limit.

 

In cases of itchy skin, itchy eyes, hives, eczema, nausea, vomiting, persistent diarrhea, sneezing, coughing, congestion, difficulty breathing, and asthma symptoms like wheezing, breathlessness, coughing, and tightness in the chest, the doctor may recommend a total IgE test.