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Each instances, I took an preliminary 20 to 40 milligram dose, after which topped up with 10 to 20 milligrams about 10 days later, with the intention to lengthen the effects into the final week of the three-week stage race and to keep away from too speedy a descent off it.
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A examine carried out in adults to judge the efficacy and safety of escalating doses of ICS demonstrated that for almost all of patients, maximal improvement in FEV1 and methacholine responsiveness occurred at low to reasonable doses of FP and BDP, with no added advantage of extremely excessive doses.64 Nevertheless, a considerable linear increase in cortisol suppression was seen as ICS dose increased.
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