GOOD Recommends Revlimid As Multiple Myeloma DifferentThe approval was further expanded in 2015 to be used together with dexamethasone to treat multiple myeloma sufferers who are not eligible for autologous hematopoietic stem cell transplant (AHSCT). The results of PFS at unblinding, following a preplanned interim analysis, utilizing a cut-off of 17 December 2009 (15.5 months comply with up) showed a sixty two% discount in threat of disease progression or loss of life favoring lenalidomide (HR = zero.38; ninety five% CI zero.27, 0.fifty four; p The National Institute for Health and Care Excellence (GOOD) beneficial the drug, lenalidomide (Revlimid), be offered in combination with the steroid dexamethasone However solely for individuals who can not take the current thalidomide-primarily based commonplace of care or aren't capable of have a stem cell transplant.
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Dexamethasone and interferon are two medication which were investigated as upkeep remedy, but advantages remain unsure. As well as, most sufferers presenting with venous or arterial thromboembolic events in affiliation with thalidomide remedy have identifiable risk factors for thromboembolism.
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