A range of factors is responsible for contributing to erectile dysfunction, which includes lifestyle choices, mental state, chronic disease, and other injuries. Emotional issues like stress and performance anxiety can also have a have an impact on both erectile performance and other sexual desire. Occasional treatment with a PDE5 inhibitor including Megalis 20 can be effective in breaking a cycle of anxiety and failure. Lifestyle factors, like smoking, non-prescription medicine consumption, excessive intake of alcohol and even obesity can have an effect. Erectile dysfunction condition in man is sometimes a symptom of underlying health problems like diabetes, atherosclerosis and heart disease, amongst others.