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Bicalutamide belongs to a gaggle of medicines referred to as nonsteroidal antiandrogens. Analyses of all key secondary finish points discovered enzalutamide to be considerably superior to bicalutamide ( Desk 2 ). Enzalutamide was associated with a lower within the threat of radiographic development or demise compared with bicalutamide in each metastatic and nonmetastatic disease: sixty eight% (HR, 0.32; 95% CI, 0.21 to zero.50; P <001; Fig 2C and Desk 2 ) and seventy six% (HR, 0.24; 95% CI, 0.10 to 0.fifty six; Table 2 ), respectively.
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