The BCG vaccine is used to protect against tuberculosis infection. In many countries with a high prevalence of tuberculosis, BCG is used to prevent tuberculosis meningitis and miliary illness in children. The vaccine’s effectiveness against adult pulmonary tuberculosis varies depending on other factors, such as the vaccine’s propensity to interfere with tuberculin skin test reactivity. This vaccine should only be considered for a small number of persons who meet specified requirements and have had extensive consultation with a tuberculosis expert Or a second opinion.