CBD or cannabidiol is deprived of psychoactive properties, but it helps with various diseases

Recently, the topic of medical marijuana has been surfacing more and more often in foreign media, scientists are trying their best to get permissions and funding for research in this area, believing in its promise, and in many countries of the world, decriminalization and legalization are underway.

Most hype now causes a substance such as CBD or cannabidiol contained in the hemp plant. Today it can be found anywhere - from food to decorative cosmetics and quite legally purchased in online stores in the form of oil. And all because CBD does not have psychoactive properties, unlike tetrahydrocannabinol (THC), but it has healing properties.

Since CBD is an active component of marijuana itself, you can get profit from it by smoking a joint in the old fashioned way. The main thing is to make sure that a grade with a predominance of this particular substance, rather than THC, is clogged in your joint if you just want to relax and relieve anxiety or pain, and not, as usual, get stuck in the couch, unsuccessfully trying to control paranoia.

Let's try to figure out how this magical cannabidiol works, based on the latest data from the world of science and the experience of consumers using CBD as a medicine, and not for fun.

Since cannabidiol is not a psychoactive substance, you can't get high from it, but it's easy to increase your productivity, relieve anxiety and relieve pain. When using CBD, thoughts are not confused, memory does not deteriorate, and as a result of muscle relaxation, you do not become a vegetable, as is often the case with smoking cannabis varieties with a predominance of THC.

If the ratio of these substances is approximately the same, then you will find a slight euphoric and the above-mentioned beneficial effects at the same time. At the same time, such negative consequences as paranoia, dry mouth, drying out and redness of the eyes, hunger and gluttony, drowsiness, and short-term memory problems, which are often caused by THC, do not occur. Such varieties are most often used as a painkiller.

Although CBD works well alone, some experts still insist that in combination with other active components of marijuana, it brings more benefits:

"To achieve a better therapeutic effect, you need a mix of cannabidiol, THC, and terpenoid phytochemicals," says psychiatrist doctor at Harvard Medical School Lester Greenspoon.

However, how exactly this effect is achieved, scientists can not yet say with accuracy. This knowledge gap is caused, first of all, by a lack of research data, since the field of studying the healing properties of hemp is botany.bio still in its infancy. But the gradual legalization of medical marijuana suggests that scientists will soon have more freedom for their experiments. So hold the fists, hope and believe.

Some scientific papers suggest that CBD has anti-inflammatory, analgesic and antipsychotic properties. In this regard, doctors hope that this substance will help pharmaceutical companies to develop effective drugs against many disorders and diseases accompanied by similar symptoms.

The list of such diseases includes, but is not limited to such pathological conditions:

So far, there are no full-fledged drugs based on CBD to combat these disorders, but many patients claim that the substance helps them to alleviate and even completely get rid of the symptoms.

Recently in the USA, where marijuana is still on the list of the most dangerous psychoactive substances, there has been a real breakthrough in the field of pharmaceuticals - the Federal Food and Drug Administration (FDA) has approved the launch of the first marijuana-based antiepileptic drug on the American market under Epidiolex name.

Its main component is precisely cannabidiol, the anticonvulsant effect of which the FDA has confirmed with its tests. Today, Epidiolex is used to treat severe forms of epilepsy and such rare disorders that cause frequent and intense cramps in children, like Drave syndrome and Lenno-Gastaut syndrome.

And yet, before Epidiolex, there were other drugs based on the components of marijuana. For example, the Belgian company Solvay Pharmaceuticals back in 1985 created Marinol (dronabinol), a medication that is simply a synthetic THC, which is still used today to increase the appetite of cancer patients undergoing chemotherapy.

In 2010, British pharmaceutical group GW Pharmaceuticals developed Sativex, a drug containing equal parts of CBD and THC, to relieve muscle cramps and other symptoms of multiple sclerosis.

Although there is still not so much data on how CBD has a beneficial effect on the body, scientists still have some ideas on this subject. Surprisingly, cannabidiol does not bind to the active sites of the cannabinoid receptors CB1 and CB2, as does the same THC. But it interacts with the GPR55 protein secreted in the brain and peripheral organs. Researchers believe that this determines its antispasmodic effect.

In the brain, CBD regulates the synaptic transmission process, during which signaling molecules are transmitted from one neuron to another. The connections between these brain cells grow stronger when GPR55 is activated.

Convulsions occur when neurons become too active in signaling, flashing more often than necessary. Cannabidiol blocks the GPR55 protein, thus preventing overload of the synaptic transmission system, according to Ben Wally, head of research at GW Pharmaceuticals.

The relationship of this protein with CBD is confirmed by experiments with genetically modified rodents in which epileptic seizures were caused. Those animals in which GPR55 was present responded to cannabidiol treatment, and rats without protein continued to experience convulsions.

Wally also believes that CBD can contribute to the desensitization of the TRPV1 protein, which is involved in the transport of ions and calcium in the body, which also helps relieve cramping. First, cannabidiol activates this protein, but then quickly decreases the sensitivity of the ion channel, effectively blocking the transport of calcium into cells. By analogy with GPR55, animals that lack TRPV1 do not respond to CBD.

Finally, this substance interacts with the channel of transport of adenosine, an anticonvulsant substance produced by the body. Wally believes that cannabidiol suppresses seizures, mainly due to its effect on adenosine, but more experiments are needed to confirm this hypothesis.

Such a wide range of areas in which CBD is active allows scientists to suggest that this substance may be useful in the treatment of motor disorders, such as Parkinson's disease. And the interaction with serotonin receptors suggests that cannabidiol can be used to treat depression, anxiety and psychotic stages of bipolar disorder and schizophrenia.

Nevertheless, many researchers, such as Roger Pertwee, a professor at the University of Aberdeen and the head of the pharmacology department of GW Pharmaceuticals, insist that without clinical data it cannot be confidently stated that the interaction of CBD with these receptors and proteins means that it causes a therapeutic effect of this substance.

Finally, we will give you a list of popular cannabidiol-dominated varieties so you know what to ask about next time in your telegram supermarket:

CBD is big news right now. What's more, CBD is a big business. It's safe to say that cannabidiol has gone mainstream. Many mainstream and boutique retailers are now carrying products containing CBD. The move into the mainstream world doesn't necessarily mean that everybody understands the ins and outs of buying and using CBD products. What does that mean for you if you sell CBD products?

Cannabidiol use is something that grew through word of mouth up until very recently. The reason for this is that the use of cannabidiol was universally stigmatized up until very recently. That may seem silly to people who use cannabidiol ointments to heal aches, pains, and health issues. However, the reality is that many people assume that cannabidiol products are illegal and dangerous. It can be hard to explain the decriminalization of cannabis to customers when you're trying to widen your customer base for CBD products. Marketing is more critical for cannabidiol vendors than any other type of vendor at this moment in time.

Cannabidiol sellers should have three goals in mind when building and deploying ad campaigns for their products. The first goal should be to clear up misconceptions that are still lingering about cannabidiol. The biggest misconception is that cannabidiol oil is illegal everywhere. One easy way to demystify your product is to distinguish between products that are derived from marijuana and products that are derived from hemp. You want to give your target audience reassurance that they won't be participating in any criminal act by purchasing your product.

The second goal of CBD advertising should be to show off the benefits of using products that contain cannabidiol. The stigma surrounding cannabidiol means that many people think they will become mentally altered after using cannabidiol products. Things like testimonials from actual users or tutorials for treating specific conditions can demonstrate the value and safety of your cannabidiol products. What's more, showing off the benefits of CBD products can help skeptical or suspicious customers to get past the stigma of using cannabidiol.

The third goal that CBD marketing should accomplish is to tell the story of cannabidiol. A CBD seller is a CBD educator by default. Campaigns that focus on how CBD oil is produced can help your target audience to see the natural, holistic qualities of this product. Customers will be reluctant to try products with CBD if they still don't have a grasp on what they are buying.

It's great if you already have a plan in mind for marketing your CBD products. Online platforms can be wonderful for getting the word out. However, the problem is that CBD marketers are still being penalized and blacklisted on many popular online advertising platforms. The good news is that you can run successful, highly visible campaigns once you know the secrets behind promoting your products without interfering with the ad policies of Google, Facebook, Instagram and other platforms. Would you like to learn how to build a campaign that attracts eyes without getting booted from ad platforms? Contact us today to learn about the best way to do CBD marketing while the market still has plenty of room for you.