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The Phase III PEACHTREE trial evaluated the company's suprachoroidal triamcinolone acetonide platform in sufferers with macular edema secondary to noninfectious uveitis.10 The examine showed that significantly more patients gained 15 letters within the Xipere-handled group (47 %) in contrast with controls (sixteen percent) at six months (p< zero.001).
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In distinction with triamcinolone acetonide CS, the formulation of triamcinolone acetonide ER allows a slower release of triamcinolone acetonide within the injection web site, not only prolonging its presence in the synovium but in addition reducing its systemic absorption (Sect.
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