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In a randomized, double-blind, clinical trial, there have been no variations in drinking outcomes in 175 patients with alcohol dependence assigned to minimal psychosocial treatment and handled with either oral naltrexone or placebo ( Chick et al., 2000 ). Nonetheless, when only these subjects demonstrating greater than 80-p.c medication compliance have been included in the analysis, oral naltrexone was found to be efficient.
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The outcomes matched a earlier examine conducted in Norway evaluating naltrexone and buprenorphine. 108 pregnant patients started naltrexone during the study period.
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