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High Pressure Jacketed Liposome Extruder | Genizer Machinery

Genizer Jacketed Liposome Extruders is compressed air driven, temperature-controlled, from testing to manufacture production of liposome and lipopolyplex for drug and gene delivery. Homogenous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. The Jacketed Extruder is virtually no dead-volume and is easily cleaned and suitable for sterilization. The Genizer Jacketed Liposome Extruders are designed to generate homogeneous unilamellar liposomes and Lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein, or gene through track-etched filters with defined pore size. It is relatively gentle, exposing the formulation to moderate pressures up to 3,000 psi at controlled temperatures. The Genizer Jacketed Extruder is easily cleaned and suitable for sterilization, compliance with FDA and GMP sanitary standards in Pharmaceuticals.

 


Unique Benefits

Genizer Jacketed Liposome Extruders is compressed air driven, temperature-controlled, from testing to manufacture production of liposome and lipopolyplex for drug and gene delivery. Homogenous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with a uniform liposome size. The Jacketed Extruder is virtually no dead-volume and is easily cleaned and suitable for sterilization.

 

 

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Sanitary: 316L Stainless Steel

l  Efficient: micron pore supporting maximize the pressure and lower the contamination

l  Compatibility: GMP and FDA compliant

 

 

 

The Genizer Jacketed Liposome Extruders are designed to generate homogeneous unilamellar liposomes and Lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein or gene through track-etched filters with defined pore size. It is relatively gentle, exposing the formulation to moderate pressures up to 3,000 psi at controlled temperatures. The Genizer Jacketed Extruder is easily cleaned and suitable for sterilization, compliance with FDA and GMP sanitary standards in Pharmaceuticals.

 

 

Catalog No.

GJE-10mL

GJE-100mL

GJE-800mL

GJE-3000mL

GJE-10000mL

Sample Size

10mL

100mL

800mL

3000mL

10000mL

Dimensions

23×13×25(cm)

23×20×32(cm)

25×25×37(cm)

30×25×55(cm)

45×40×65(cm)

Weight

4kg

7kg

20kg

45kg

120kg

Min. Sample Size

5mL

10mL

100mL

800mL

2000mL

 

Max. Pressure

 

 

 

3,000psi-6,000psi

 

 

Power Type

 

Compressed Gas

 

 

 

Nano-Membrane

 

 

 

 

Track etched liposome membrane

 

 

                   High-Pressure Jacketed Liposome Extruder

 

 

Standard Feature

 

 

Parts                          1) Liposome Jacketed Extruder 2) 10 Pieces of 100nm membrane

Feed Reservoir           Temperature control jacketed cylinder

Nitrogen tubing          G5/8"- 14 TPI BSP inlet Nitrogen High-Pressure soft tubing; adaptor with 3/8                                       inch male NPT and 1/4 inch female flare outlet

Nano Membrane        100nm track-etched polycarbonate membrane

Compatibility              Some Parts are compatible with lipex TM in Northern Lipids

Product Material        316L Stainless Steel, Viton

Material Standard         Pharmaceutical Grad, FDA & GMP approvable 

Warranty                       1 Year against any manufacturing defects

 

               

                                                                       



 

Available Option

Detecter          Pressure gauge,Pressure Temperature Transducer

Inlet Type            Tri-clamp or luer

Nano Membrane   30, 50, 80, 100, 200, 400, 800nm, 2μm, 5μm, 10μm, 20μm, 30μm, track-etched                                                 membrane

Multi Extruder      Parallel or series connection of Multi Excruder

 

 

    

                                                                       

 

 

If you are looking high pressure homogenizer manufacturer companies and suppliers that offer the reasonable price? You can find leading companies details here :

Phone: +1(323) 825-1851

Fax    : +1(323) 978-4693

Email: Nano@Genizer.com  http://www.genizer.com/high-pressure-transmitter-for- multi-purpose_p0037.html

 

Discount available for public research. Genizer.com reserves the right to change specifications without notice. 

 

 

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