Immunosuppression is the decreased capacity to neutralize external organisms, which may result in repeated more severe or prolonged infections and increased susceptibility to cancer development. Immunosuppressive therapy is mainly used to aid organ transplants. The first stage of the development in immunosuppression introduced in the late 1950s and early 1960s consisted of using cytostatic drugs(antineoplastics) and antimetabolites (methotrexate, azathioprine, cyclophosphamide, chlorambucil)which were used to control the proliferation of neoplastic cells. A significant risk of immunosuppressive drugs is an infection as the immune system is suppressed and not able to fight infections effectively... Read More
