New research study recommends the ketogenic or keto diet plan might show useful in helping treat some kinds of AlkaTone cancer by boosting the effectiveness of chemotherapy and other drugs.
The secret to success is keeping blood sugar level under control. The keto diet does simply that by limiting carbs to a minimum.
It consists of high fat foods and also contains foods with an adequate amount of protein and an extremely low quantity of carbs. Glucose is derived from sugar that is present in carbohydrates.
The method the keto diet works and the factor why it's being thought about as part of a therapy to cure some forms of cancer, is that it denies the body of glucose. This glucose deprivation induces a state called "ketosis.".
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In ketosis, the body is forced to use stored fat in the kidneys instead of sugar to produce an alternative source of energy.
A brand-new research study explores the keto diet plan as a potential opportunity for treatment of specific types of cancer. A group of researchers from the University of Texas at Dallas limited the levels of circulating glucose in mice by feeding them a ketogenic diet and administering a diabetes drug that stops the reabsorption of blood sugar level in the kidneys.
The scientists released their paper in the journal Cell Reports. An assistant professor of biological sciences at the University of Texas at Dallas, Jung-Whan Kim, is the corresponding author of the brand-new study while Meng-Hsiung Hsieh is the very first author.
Formerly, a cancer type called squamous cell cancer (SCC) relies heavily on glucose to sustain its "antioxidative capability and survival" compared to other kinds of cancers, according to Kim and his group.
The group reasoned restricting glucose needs to make SCC more vulnerable to treatment. To test this theory, they fed mice with xenograft tumors with either a ketogenic diet consisting of 0.1% carbohydrates or a regular diet plan.
" Xenograft tumor growth of lung SCC [...] and esophageal SCC [...] was substantially inhibited upon ketogenic diet as compared to typical chow fed groups," stated the study.
Kim kept in mind that both the ketogenic diet plan and the pharmacological limitation of blood sugar by themselves inhibited the further growth of SCC tumors in mice with lung cancer. On the other hand, the glucose constraint did not impact non-SCC tumors.
" While these interventions did not shrink the tumors, they did keep them from advancing, which recommends this type of cancer might be susceptible to glucose constraint.".
Kim stated their outcomes recommend this approach is "cancer cell type specific. We can not generalize to all kinds of cancer.".
Kim stated the key finding of their brand-new study in mice is that a ketogenic diet alone does have some tumor growth inhibitory result in SCC. However when the team combined this with a diabetes drug and chemotherapy, the treatment was a lot more effective.
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