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Passive immunisation with varicella-zoster immunoglobulin is needed for exposed non-immune patients receiving systemic corticosteroids or for those who have used them inside the earlier three months; varicella-zoster immunoglobulin should ideally be given inside three days of exposure and never later than 10 days.
Following native injection, reduction of pain and swelling and higher freedom of motion are usually obtained inside just a few hours; such administration avoids the more severe systemic side-effects which can accompany parenteral or oral corticosteroid administration.
It's not identified whether topical administration of corticosteroids could lead to adequate systemic absorption to provide detectable quantities in breast milk Systemically administered corticosteroids are secreted into breast milk in quantities not prone to have a deleterious impact on the toddler.
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