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There have been instances reported by which concomitant use of amphotericin B and hydrocortisone was adopted by cardiac enlargement and congestive heart failure.Antibiotics: Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance.Anticholinesterases: Concomitant use of anticholinesterase agents and corticosteroids might produce severe weakness in patients with myasthenia gravis.
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